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Government, defense and large corporate AI teams. 16 verified listings in the St. Louis metro, including Center for Health AI (WashU Medicine and BJC), Edward Jones (Gen AI program and Ventures) and Enabled Intelligence.
St. Louis, MO · Local office
Vantor, formerly Maxar Intelligence, is a geospatial intelligence firm whose AI-powered platform includes Sentry change detection and Raptor navigation for places without GPS.
View profileVerifiedSt. Louis, MO · Local office
Enabled Intelligence provides AI and machine learning data labeling for national security agencies, with a largely neurodivergent workforce.
View profileVerifiedSt. Louis, MO · Local office
Scale AI's St. Louis AI Center hires and trains Missourians to do geospatial and generative AI data work for the U.S. government.
View profileVerifiedSt. Louis, MO
T-REX is a downtown innovation center and geospatial hub that houses NGA's Moonshot Labs software factory and accelerator.
View profileVerifiedSt. Louis, MO
Nonprofit backbone organization, launched in 2026 from the GeoFutures roadmap, that coordinates the St. Louis geospatial and GeoAI economy and administers the Spirit of St. Louis AI Innovation Center and its AI competitions.
View profileVerifiedSt. Louis, MO
Saint Louis University's Geospatial Center is a university-wide center for GeoAI, quantum sensing and geospatial analytics research.
View profileVerifiedSt. Louis, MO · Local office
NGA's GAIA Lab at Moonshot Labs lets St. Louis-area students do AI geoscience research alongside NGA scientist mentors.
View profileVerifiedSt. Louis, MO
The Center for Health AI, run by WashU Medicine and BJC Health System, builds and tests AI for patient care, hospital operations and clinical workflows.
View profileVerifiedSt. Louis, MO
Edward Jones runs an in-house generative AI skills program built on its Mack tool, and its venture arm invests in fintech startups.
View profileVerifiedSt. Louis, MO
St. Louis IT services firm offering data, AI and machine learning services, including AI-driven analytics and data governance, and labeled AI training datasets built through its Simpack-Edge joint venture for a national security AI program.
View profileVerifiedSt. Louis, MO
St. Louis-based health insurer that uses AI in administrative communications with members and is exploring interactive AI tools to help Medicaid patients and rural community health workers with early steps in care.
View profileVerifiedSt. Louis, MO
St. Louis-headquartered automation company whose industrial AI portfolio, including AspenTech tools, Aspen Virtual Advisor and the Project Beyond platform, helps manufacturers design plants, modernize control systems and move toward autonomous operations.
View profileVerifiedChesterfield, MO
Chesterfield-based health system running more than 200 AI models, using Aidoc imaging AI to flag findings, Microsoft DAX Copilot for ambient visit notes, and AI tools for nurse handoffs and virtual nursing.
View profileVerifiedScott Air Force Base, IL
Defense logistics command headquartered at Scott Air Force Base that builds AI tools with MIT Lincoln Laboratory for patient movement and mass casualty response, and in 2026 used AI agents to plan airfield capacity and maintenance.
View profileVerifiedScott Air Force Base, IL
Air Force major command at Scott Air Force Base that uses AI to consolidate data for leaders, analyze exercise observations, pull lessons learned from operational messages and support war-gaming for air mobility operations.
View profileVerifiedSt. Louis, MO
Taylor Geospatial is a St. Louis nonprofit that develops and commercializes geospatial AI, with a focus on open science.
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